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Traumatic brain injury in mice and pentadecapeptide BPC 157 effect - ScienceDirect

S1PR1 expression increased following cuprizone withdrawal in WT ( p = 0.004 comparing 6W to 6+2W) but not SphK2 -/- mice, and was significantly lower in the 6+2W SphK2 -/- compared to the 6+2W WT group ( p = 0.002)

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Upregulates growth factors such as VEGF (vascular endothelial growth factor) and FGF (fibroblast growth factor), accelerating wound repair